A Common Diaryl Ether Intermediate for the Gram‐Scale Synthesis of Oxazine and Xanthene Fluorophores

Abstract
Common ground: Copper‐catalyzed coupling reactions can be used for the high‐yielding preparation of widely used oxazine and xanthene fluorophores from a common diaryl ether intermediate on a gram‐scale (see scheme). This general approach may facilitate the future development of novel fluorophores and probes with unique properties.