Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex–mediated inflammation in mice
- 20 August 2015
- journal article
- Published by American Society of Hematology in Blood
- Vol. 126 (8), 1017-1026
- https://doi.org/10.1182/blood-2014-12-617159
Abstract
Key Points GPVI-dependent platelet binding and activation contribute to seal neutrophil-induced vascular damage in IC-mediated inflammation. Inflammation represents an uncommon hemostatic situation in which adhesion and activation of single platelets prevent bleeding.Keywords
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