Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice
Open Access
- 7 February 2013
- journal article
- Published by American Society of Hematology in Blood
- Vol. 121 (6), 1008-1015
- https://doi.org/10.1182/blood-2012-06-437392
Abstract
Key Points During inflammation, serotonin released by platelets activates vessel wall promoting leukocyte adhesion and recruitment. Absence of platelet serotonin improves survival after lipopolysaccharide-induced endotoxic shock.Keywords
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