Isolation and Characterization of 1,3-Dicapryloyl-2-linoleoylglycerol: A Novel Triglyceride from Berries of Hippophae rhamnoides
Open Access
- 1 January 2005
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 53 (8), 1021-1024
- https://doi.org/10.1248/cpb.53.1021
Abstract
1,3-Dicapryloyl-2-linoleoylglycerol (1), a novel triglyceride, was isolated from berries of Hippophae rhamnoides. The structure was elucidated on the basis of MS, 1D and 2D NMR experiments including HMQC and HMBC. The metal chelating, free radical scavenging, and lipid peroxidation inhibiting properties of the compound were also estimated with particular reference to radiation protection. In case of metal chelation and superoxide ion scavenging, 1 showed maximum inhibition at 50 μg/ml (11%) and 100 μg/ml (55%), respectively, whereas in lipid peroxidation, 1 showed maximum inhibition (57%) at 2 mg/ml as compared to quercetin as a control.Keywords
This publication has 13 references indexed in Scilit:
- Radioprotection by plant products: present status and future prospectsPhytotherapy Research, 2005
- Essential oil and fatty acid composition of the fruits of Hippophae rhamnoides L. (Sea Buckthorn) and Myrtus communis L. from TurkeyBiochemical Systematics and Ecology, 2004
- Distribution and Contents of Phenolic Compounds in Eighteen Scandinavian Berry SpeciesJournal of Agricultural and Food Chemistry, 2004
- Structural Investigations of Flavonol Glycosides from Sea Buckthorn (Hippophaë rhamnoides) Pomace by NMR Spectroscopy and HPLC-ESI-MSnJournal of Agricultural and Food Chemistry, 2004
- Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humansThe Journal of Nutritional Biochemistry, 2002
- Radioprotection by a herbal preparation of Hippophae rhamnoides, RH-3, against whole body lethal irradiation in micePhytomedicine, 2002
- Mosquitocidal Compounds and a Triglyceride, 1,3-Dilinoleneoyl-2-palmitin, from Ocimum sanctumJournal of Agricultural and Food Chemistry, 1998
- Characterization of pit oil from Montmorency cherry (Prunus cerasus L.)Journal of Agricultural and Food Chemistry, 1993
- Tannins from Hippophae rhamnoidesPhytochemistry, 1991
- Bidentate ChelatesPublished by Elsevier BV ,1964