RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population
Open Access
- 17 July 2008
- journal article
- Published by Springer Science and Business Media LLC in BMC Cardiovascular Disorders
- Vol. 8 (1), 15
- https://doi.org/10.1186/1471-2261-8-15
Abstract
Several polymorphisms within the renin-angiotensin system cluster of genes have been associated with the advent of coronary artery disease (CAD) or related pathologies. We investigated the distribution of 5 of these polymorphisms in order to find any association with CAD development and distinguish if any of the biochemical and behavioural factors interact with genetic polymorphisms in the advent of the disease.Keywords
This publication has 44 references indexed in Scilit:
- The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemiaEuropean Journal of Epidemiology, 2008
- Modification of the Coronary Artery Disease Risk Associated with the Presence of Traditional Risk Factors by Insertion/Deletion Polymorphism of theACEGeneGenetic Testing, 2007
- Angiotensin-converting enzyme and p22phox polymorphisms and the risk of coronary heart disease in a low-risk Spanish populationInternational Journal of Cardiology, 2004
- Sex Difference in the Effect of ACE-DD Genotype on the Risk of Premature Myocardial InfarctionAngiology, 2004
- Prospective evaluation of the effect of an angiotensin I converting enzyme gene polymorphism on the long term risk of major adverse cardiac events after percutaneous coronary interventionHeart, 2003
- Large-scale test of hypothesised associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controlsThe Lancet, 2000
- Angiotensinogen Gene Polymorphisms M235T/T174MHypertension, 1999
- Angiotensin-converting enzyme and angiotensin II receptor 1 polymorphisms: association with early coronary diseaseCardiovascular Research, 1998
- Significance of angiotensin I-converting enzyme and angiotensin II type 1 receptor gene polymorphisms as risk factors for coronary heart diseaseAtherosclerosis, 1996
- Enhanced Predictability of Myocardial Infarction in Japanese by Combined Genotype AnalysisHypertension, 1995