Antioxidant and antimicrobial properties of 2-(4,5-dihydro-1H-pyrazol-1-yl)-pyrimidine and 1-carboxamidino-1H-pyrazole derivatives
Open Access
- 1 January 2010
- journal article
- research article
- Published by FapUNIFESP (SciELO) in Journal of the Brazilian Chemical Society
- Vol. 21 (8), 1477-1483
- https://doi.org/10.1590/s0103-50532010000800010
Abstract
Five previously synthesized 4-trifluoromethyl-2-(5-aryl-3-styryl-1H-pyrazol-1yl)-pyrimidines and six 5-aryl-3-styryl-1-carboxamidino-1H-pyrazole derivatives were screened for their antioxidant proprieties. The antioxidant activities were evaluated by using the DPPH and the HRP/luminol/H(2)O(2) chemiluminescence assay systems and for their antimicrobial activity (MIC). The results were good for those series in some concentration in comparison with the standards.This publication has 7 references indexed in Scilit:
- Novel Regiospecific Method for Synthesis of 2‐(3,5‐Diaryl‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)‐4,6‐diarylpyrimidinesSynthetic Communications, 2008
- Counterfeit or substandard antimicrobial drugs: a review of the scientific evidenceJournal of Antimicrobial Chemotherapy, 2007
- Synthesis of New 2-(5-Aryl-3-styryl-4,5-dihydro-1H-pyrazol-1-yl)-4-(trifluoromethyl)pyrimidinesSynthesis, 2006
- Modified 2,2-Azino-bis-3-ethylbenzothiazoline-6-sulfonic Acid (ABTS) Method to Measure Antioxidant Capacity of Selected Small Fruits and Comparison to Ferric Reducing Antioxidant Power (FRAP) and 2,2‘-Diphenyl-1-picrylhydrazyl (DPPH) MethodsJournal of Agricultural and Food Chemistry, 2006
- Synthesis and In Vitro Antioxidant Activity of some New Fused Pyridine AnalogsArchiv der Pharmazie, 2005
- Biopolyphenolics as antioxidants: Studies under an Indo-Italian CSIR-CNR projectPure and Applied Chemistry, 2005
- Synthesis and GABA receptor potency of 3-thiomethyl-4-(hetero)aryl-5-amino-1-phenylpyrazolesBioorganic & Medicinal Chemistry Letters, 2004