Antioxidant activity of flower, stem and leaf extracts of Ferula gummosa Boiss
Open Access
- 28 April 2010
- journal article
- Published by Editorial CSIC in Grasas y Aceites
- Vol. 61 (3), 244-250
- https://doi.org/10.3989/gya.110809
Abstract
The Antioxidant and antihemolytic activities of hydroalcoholic extracts of the flowers, stems and leaves of the Ferula gummosa Boiss were investigated employing different in vitro assay systems. Leaf extract showed better activity in DPPH radical scavenging. In addition it showed better activity in nitric oxide and H2O2 scavenging and Fe2+ chelating activity than the other parts. The extracts exhibited good antioxidant activity in linoleic acid system test but were not comparable with vitamin C (p< 0.001). The extracts showed weak reducing power activity. The F. gummosa stem extract showed better antihemolytic activity against H2O2 induced hemolysis. Among the extracts, the flowers had higher phenolic and flavonoid contents. This plant is very promising for further biochemical experiments. La actividad antihemolítica y antioxidante de extractos hidroalcohólicos de flores, tallos y hojas de Ferula gummosa Boiss fueron investigados empleando diferentes ensayos in vitro. Los extractos de hojas mostraron una mejor actividad captadora de radicales libres. Además, mostraron una mejor actividad captadora de óxido nítrico y H2O2 y actividad quelatante de Fe2+ que las otras partes. Los extractos exhibieron una buena actividad antioxidante en el ensayo con ácido linoleico pero no comparable con la vitamina C (p< 0.001). Los extractos mostraron una débil actividad de poder reductor. Los extractos de tallos de F. gummosa mostraron una mejor actividad antihemolítica contra la hemolisis inducida con H2O2. Entre los extractos, las flores tienen los más altos contenidos de fenoles y flavonoides. Esta planta es muy prometedora para futuros experimentos bioquímicosKeywords
This publication has 22 references indexed in Scilit:
- Antihypoxic and antioxidant activity of Hibiscus esculentus seedsGrasas y Aceites, 2009
- Essential oil Composition and Antioxidant Activity of Pterocarya fraxinifoliaPakistan Journal of Biological Sciences, 2009
- Antioxidant activity of the methanol extract of Ferula assafoetida and its essential oil compositionGrasas y Aceites, 2009
- Interaction of flavonoids with red blood cell membrane lipids and proteins: Antioxidant and antihemolytic effectsInternational Journal of Biological Macromolecules, 2007
- Protection from oxidative damage using Bidens pilosa extracts in normal human erythrocytesFood and Chemical Toxicology, 2006
- Antibacterial activity of the essential oil from Ferula gummosa seedFitoterapia, 2004
- Spasmolytic activity of essential oil and various extracts of Ferula gummosa Boiss. on ileum contractionsPhytomedicine, 2001
- Structural aspects of antioxidant activity of flavonoidsFree Radical Biology & Medicine, 1996
- Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?The Lancet, 1994
- Toxicity and carcinogenicity studies of quercetin, a natural component of foodsFundamental and Applied Toxicology, 1992