Synthesis and physico-chemical studies of metal(II) complexes with diacetyl benzaldehyde acyldihydrazones and their bio-activity
- 15 November 2008
- journal article
- research article
- Published by Taylor & Francis Ltd in Journal of Coordination Chemistry
- Vol. 61 (24), 3922-3933
- https://doi.org/10.1080/00958970802160974
Abstract
Complexes of Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) with diacetyl benzaldehyde oxalic acid dihydrazone (dbodh), CH3COC(CH3)=NNHCOCONHN=CHC6H5 and diacetyl benzaldehyde malonic acid dihydrazone (dbmdh), CH3COC(CH3)=NNHCOCH2CONHN=CHC6H5 of general composition [M(dbodh)Cl]Cl and [M(dbmdh)Cl]Cl were synthesized and characterized by microanalyses, molar conductance, magnetic susceptibility, UV–Vis, ESR and IR spectra and X-ray diffraction studies. The complexes are 1 : 1 electrolytes in DMF and are insoluble in water and common organic solvents. The dbodh and dbmdh are neutral tridentate ligands in most complexes and coordinate via one >C=O and two >C=N–groups. In Cu(II) complexes the ligands are pentadentate coordinating through three >C=O and two >C=N–groups. The magnetic moment values and UV–Vis spectra suggest square-planar geometry for Co(II) and Ni(II) complexes and distorted octahedron for both Cu(II) complexes. The ESR spectra of Cu(II) complexes show well-defined copper hyperfine lines in DMSO solution at 120 K and exhibit d x 2 −y 2 as the ground state. The X-ray diffraction parameters for [Ni(dbodh)Cl]Cl and [Co(dbmdh)Cl]Cl correspond to a tetragonal crystal lattice. The complexes show significant antifungal activity against Alternaria sp., Curvularia sp. and Colletotrichum sp. and fair antibacterial activity against Bacillus subtilis and Pseudomonas fluorescence.Keywords
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