Synthesis, Characterization, Electrical Conductance, Thermal Decomposition, X-Ray Diffraction Studies, and Biological Activity of Aluminum(III) Complexes with Acylhydrazines

Abstract

Aluminum(III) complexes of the type [AlL₂X₂]X˙n H₂O where L = isonicotinoyl hydrazine (INH), NC₅H₄CONHNH₂, salicyloyl-hydrazine (SH), HOC₆H₄CONHNH₂, oxaloyldihydrazine (ODH), (CONHNH₂)₂, and malonoyldihydrazine (MDH), CH₂(CONHNH₂)₂; X = CL⁻, NO₃ ⁻, SCN⁻ and 1/2 SO₄ ^2-; n = 0–3, were prepared and characterized with the help of elemental analyses, solution and solid state conductance, thermal decomposition and infrared spectral studies. All the complexes are insoluble in common organic solvents and most of them are stable upto 300°C, above which they show stepwise decomposition patterns. Solid state conductance data at room temperature suggest semiconducting properties of the complexes. IR spectra indicate that the ligands bond to the metal atom through >C=O and -NH₂ groups. X-ray diffraction parameters of [Al(SH)₂Cl₂]Cl. 2H₂O and [Al(INH)(NO₃)₂]NO₃˙2H₂O correspond to orthorhombic and tetragonal crystal lattices, respectively. The ligands as well as their complexes show moderate antifungal and antibacterial activity.