Prostate Carcinoma: Diffusion-weighted Imaging as Potential Alternative to Conventional MR and C-Choline PET/CT for Detection of Bone Metastases
- 1 December 2008
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 249 (3), 1017-1025
- https://doi.org/10.1148/radiol.2492080038
Abstract
In a technical development study approved by the institutional ethics committee, the feasibility of fast diffusion-weighted imaging as a replacement for conventional magnetic resonance (MR) imaging sequences (short inversion time inversion recovery [STIR] and T1-weighted spin echo [SE]) and positron emission tomography (PET)/computed tomography (CT) in the detection of skeletal metastases from prostate cancer was evaluated. MR imaging and carbon 11 ((11)C) choline PET/CT data from 11 consecutive prostate cancer patients with bone metastases were analyzed. Diffusion-weighted imaging appears to be equal, if not superior, to STIR and T1-weighted SE sequences and equally as effective as (11)C-choline PET/CT in detection of bone metastases in these patients. Diffusion-weighted imaging should be considered for further evaluation and comparisons with PET/CT for comprehensive whole-body staging and restaging in prostate and other cancersKeywords
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