Diffusion‐weighted MRI (DWI) in the oncology patient: Value of breathhold DWI compared to unenhanced and gadolinium‐enhanced MRI
- 2 March 2007
- journal article
- research article
- Published by Wiley in Journal of Magnetic Resonance Imaging
- Vol. 25 (4), 848-858
- https://doi.org/10.1002/jmri.20864
Abstract
Purpose To evaluate the feasibility and added value of single breathhold diffusion‐weighted (DW) imaging (DWI) in oncology patients undergoing abdominal MRI. Materials and Methods A total of 169 patients with malignancy underwent abdominal MRI at 1.5T, including T1‐weighted (T1W), T2‐weighted (T2W), and dynamic gadolinium‐enhanced imaging. Axial DWI was performed with a single‐shot spin‐echo (SE) echo‐planar imaging (EPI) sequence using a b‐value of 500 seconds/mm2. A total of 24 slices were obtained during a 20‐second breathhold. Two observers reviewed the conventional MR images for tumor. Next, the DW images were reviewed for additional tumor not depicted on conventional MR images Results For the 169 patients, additional tumors were noted on the DW images in 77 (0.46) for observer 1 and 67 (0.40) for observer 2. For observer 1 the additional tumor included lymphadenopathy (47), peritoneal metastases (15), renal (1), liver (12), and osseous (2), while for observer 2 the corresponding values were lymphadenopathy (40), peritoneal (12), renal (1), liver (6), osseous (4), and gastrointestinal (1). The DW images resolved as benign findings noted on the conventional MR images in three patients for observer 1 and four patients for observer 2. The conventional MR exam was entirely normal while the DW images showed tumor in 12 (0.07) patients for observer 1 and 10 (0.06) patients for observer 2. Conclusion DWI is feasible in a single breathhold and provides additional clinically important information in oncology patients when added to routine abdominal MR sequences. J. Magn. Reson. Imaging 2007.Keywords
This publication has 16 references indexed in Scilit:
- Can a single‐shot black‐blood T2‐weighted spin‐echo echo‐planar imaging sequence with sensitivity encoding replace the respiratory‐triggered turbo spin‐echo sequence for the liver? an optimization and feasibility studyJournal of Magnetic Resonance Imaging, 2005
- Diffusion-weighted Single Shot Echo Planar Imaging of Colorectal Cancer Using a Sensitivity-encoding TechniqueJapanese Journal of Clinical Oncology, 2004
- Diffusion-weighted MRI in the evaluation of renal lesions: preliminary resultsThe British Journal of Radiology, 2004
- Endorectal diffusion‐weighted imaging in prostate cancer to differentiate malignant and benign peripheral zone tissueJournal of Magnetic Resonance Imaging, 2004
- Single breath‐hold diffusion‐weighted imaging of the abdomenJournal of Magnetic Resonance Imaging, 2003
- Evaluation of Liver Diffusion Isotropy and Characterization of Focal Hepatic Lesions with Two Single-Shot Echo-planar MR Imaging Sequences: Prospective Study in 66 PatientsRadiology, 2003
- In vivo measurement of the apparent diffusion coefficient in normal and malignant prostatic tissues using echo-planar imagingJournal of Magnetic Resonance Imaging, 2002
- MR diffusion-weighted imaging of kidney: Differentiation between hydronephrosis and pyonephrosisClinical Imaging, 2001
- Diffusion-weighted single-shot echoplanar MR imaging for liver disease.American Journal of Roentgenology, 1999
- Invited. Ultrafast MR imaging of the abdomen: Echo planar imaging and diffusion‐weighted imagingJournal of Magnetic Resonance Imaging, 1998