Studies on Nucleotide Chemistry 15. Synthesis of Oligodeoxynucleotides Using Amidine Protected Nucleosides
- 1 February 1985
- journal article
- plenary lectures
- Published by Taylor & Francis Ltd in Nucleosides and Nucleotides
- Vol. 4 (1-2), 95-105
- https://doi.org/10.1080/07328318508077833
Abstract
An in situ method is described for synthesizing DNA which incorporates a new series of amidine protected deoxy-nucleosides and bis-dialkylaminophosphines as phosphitylating agents. These procedures were used to synthesize d(GGGAATTCCC) which was digested by EcoRI.Keywords
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