Dialkylformamldines: depurination resistant N6-protecting group for deoxyadenosine
- 1 January 1983
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 11 (22), 8031-8036
- https://doi.org/10.1093/nar/11.22.8031
Abstract
Sterically hindered N6-dialkylformamidine protected deoxyadenosine is more stable to acidic depurination than N6-benzoyldeoxyadenosine and is potentially a valuable protecting group in the synthesis of deoxyoligonucleotides.Keywords
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- Synthesis of oligodeoxyribonucleotides on silica gel supportNucleic Acids Research, 1981
- Selective n-debenzoylation of n,o-polybenzoylnucleosidesTetrahedron Letters, 1968