Emerging principles in protease-based drug discovery
Top Cited Papers
- 1 September 2010
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Reviews Drug Discovery
- Vol. 9 (9), 690-701
- https://doi.org/10.1038/nrd3053
Abstract
No abstract availableKeywords
This publication has 121 references indexed in Scilit:
- Identification of broad-based HIV-1 protease inhibitors from combinatorial librariesBiochemical Journal, 2010
- Inhibition of a viral enzyme by a small-molecule dimer disruptorNature Chemical Biology, 2009
- Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disordersNature Reviews Drug Discovery, 2009
- Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes)Biochemical Journal, 2008
- An Engineered Protease that Cleaves Specifically after Sulfated TyrosineAngewandte Chemie, 2008
- Recent advances in understanding the molecular basis of group BStreptococcusvirulenceExpert Reviews in Molecular Medicine, 2008
- Perspectives on NMR in drug discovery: a technique comes of ageNature Reviews Drug Discovery, 2008
- Identification of a New Class of Nonpeptidic Inhibitors of CruzainJournal of the American Chemical Society, 2008
- Highly active and selective endopeptidases with programmed substrate specificitiesNature Chemical Biology, 2008
- Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the familyEMBO Reports, 2006