Rhabdoid meningioma: Rapid intraoperative diagnosis on squash smears
- 20 July 2010
- journal article
- case report
- Published by Wiley in Diagnostic Cytopathology
- Vol. 38 (8), 594-596
- https://doi.org/10.1002/dc.21276
Abstract
Rhabdoid morphology in tumors refers to resemblance of the cells to rhabdomyoblasts without true skeletal muscle differentiation. The cytological features include abundant eosinophilic cytoplasm, eccentric nuclei, and intracytoplasmic hyaline inclusions. Besides the rhabdoid morphology, cytoarchitectural features of atypical meningioma (four or more mitoses per 10 high‐power fields, high cellularity, sheeting architecture, nuclear atypia, and necrosis) are seen in most cases. A case is presented here to highlight the appearance of rhabdoid cells on intraoperative squash smears, for most accurate treatment and close follow‐up, as rhabdoid morphology is related to aggressive behavior and poor outcomes. Diagn. Cytopathol. 2010;38:594–596. 2009 Wiley‐Liss, Inc.Keywords
This publication has 6 references indexed in Scilit:
- Rhabdoid meningioma: Intraoperative diagnosis using smear preparationDiagnostic Cytopathology, 2003
- Recurrent Rhabdoid Meningioma: Case ReportJournal of Neurological Surgery Part B: Skull Base, 2003
- High Diagnostic Accuracy of Cytologic Smears of Central Nervous System TumorsActa Cytologica, 2002
- "Rhabdoid" MeningiomaThe American Journal of Surgical Pathology, 1998
- Rhabdoid Transformation of Tumor Cells in MeningiomasThe American Journal of Surgical Pathology, 1998
- Intraoperative diagnosis of nervous system lesions.Acta Cytologica, 1998