Plasmodium vivax resistance to chloroquine (R2) and mefloquine (R3) in Brazilian Amazon region
Open Access
- 1 February 1999
- journal article
- case report
- Published by FapUNIFESP (SciELO) in Revista da Sociedade Brasileira de Medicina Tropical
- Vol. 32 (1), 67-68
- https://doi.org/10.1590/s0037-86821999000100013
Abstract
We report for the first time a patient with malaria due to Plasmodium vivax who showed R2 resistance to chloroquine and R3 resistance to mefloquine in the Brazilian Amazon region based on WHO clinical criteria for diagnosis of malaria resistance. Failure was observed with unsupervised oral chloroquine, chloroquine under rigorous supervision and mefloquine in the same scheme. Finally, the patient was cured with oral artesunate.Keywords
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