In Vivo Tracking Techniques for Cellular Regeneration, Replacement, and Redirection
- 9 November 2012
- journal article
- research article
- Published by Society of Nuclear Medicine in Journal of Nuclear Medicine
- Vol. 53 (12), 1825-1828
- https://doi.org/10.2967/jnumed.112.106146
Abstract
Cellular therapy can be defined as the transplantation of living cells for the treatment of medical conditions. Three main objectives of cellular therapy are regeneration of damaged tissue, replacement of function by secretion of biologically active molecules, and redirection of aberrant processes. Given the complex nature of these approaches, in vivo tracking of the transplanted cells is critical to evaluate their potential benefit and to optimize treatment strategies. Recent advances are reviewed that enable in vivo cell tracking as an important adjunct to implement cellular therapy in clinical practice.Keywords
This publication has 24 references indexed in Scilit:
- Adoptive immunotherapy for cancer: harnessing the T cell responseNature Reviews Immunology, 2012
- Stem cell treatment for acute myocardial infarctionPublished by Wiley ,2012
- [ 18 F]FDG Labeling of Neural Stem Cells for in Vivo Cell Tracking with Positron Emission Tomography: Inhibition of Tracer Release by PhloretinMolecular Imaging, 2012
- Positron Emission Tomography Reporter Genes and Reporter Probes: Gene and Cell Therapy ApplicationsTheranostics, 2012
- Stem cell technology for neurodegenerative diseasesAnnals of Neurology, 2011
- Stem Cell Tracking in Human Trials: A Meta-RegressionStem Cell Reviews and Reports, 2011
- Magnetic Resonance Imaging of Pancreatic Islets Transplanted Into the Liver in HumansTransplantation, 2010
- Imaging of cellular therapiesAdvanced Drug Delivery Reviews, 2010
- In Vivo MRI Cell Tracking: Clinical StudiesAmerican Journal of Roentgenology, 2009
- Clinical Magnetic Resonance Imaging of Pancreatic Islet Grafts After Iron Nanoparticle LabelingAmerican Journal of Transplantation, 2008