Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells
Open Access
- 1 May 2019
- journal article
- research article
- Published by Elsevier BV in Cell Reports
- Vol. 27 (6), 1858-1874.e6
- https://doi.org/10.1016/j.celrep.2019.04.037
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health
- National Science Foundation
- National Institutes of Health
- Marie Curie
This publication has 95 references indexed in Scilit:
- Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiationNature Immunology, 2013
- Endogenous antigen tunes the responsiveness of naive B cells but not T cellsNature, 2012
- A unifying model for mTORC1-mediated regulation of mRNA translationNature, 2012
- mTOR Signaling in Growth Control and DiseaseCell, 2012
- Metabolic pathways in T cell fate and functionTrends in Immunology, 2012
- The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2Nature Immunology, 2011
- The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and MetabolismImmunity, 2010
- CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic DevelopmentImmunity, 2010
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage CommitmentImmunity, 2009
- Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid CellsCell, 2009