mTOR Signaling in Growth Control and Disease
Top Cited Papers
Open Access
- 13 April 2012
- journal article
- review article
- Published by Elsevier BV in Cell
- Vol. 149 (2), 274-293
- https://doi.org/10.1016/j.cell.2012.03.017
Abstract
No abstract availableKeywords
This publication has 178 references indexed in Scilit:
- 4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in TumorsCancer Cell, 2010
- Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino AcidsCell, 2010
- Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4ECancer Cell, 2010
- 4E-BP Extends Lifespan upon Dietary Restriction by Enhancing Mitochondrial Activity in DrosophilaCell, 2009
- Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cellsBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2009
- DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their SurvivalCell, 2009
- mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in MiceCancer Cell, 2009
- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR SignalingCell, 2008
- Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycinCancer Cell, 2006
- Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progressionCell, 1993