Solution‐Phase Synthesis of Phosphorothioate Oligonucleotides Using a Solid‐Supported Acyl Chloride with H‐Phosphonate Chemistry
- 2 January 2006
- journal article
- Published by Wiley in European Journal of Organic Chemistry
- Vol. 2006 (2), 436-448
- https://doi.org/10.1002/ejoc.200500547
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- High-Yield Solution-Phase Synthesis of Di- and Trinucleotide Blocks Assisted by Polymer-Supported ReagentsOrganic Letters, 2005
- Solution phase synthesis of ISIS 2922 (Vitravene) by the modified H-phosphonate approachJournal of the Chemical Society, Perkin Transactions 1, 2002
- The chemical synthesis of oligo- and poly-nucleotides: a personal commentaryTetrahedron, 2002
- The Dimethoxytrityl Resin Product Anchored Sequential Synthesis Method (DMT PASS): A Conceptually Novel Approach to Oligonucleotide SynthesisOrganic Process Research & Development, 2000
- First synthesis of H-phosphonate oligonucleotides bearing N-unmodified basesTetrahedron Letters, 1999
- HELP (High Efficiency Liquid Phase) new oligonucleotide synthesis on soluble polymeric supportNucleic Acids Research, 1990
- Rates and mechanisms of hydrolysis of esters of phosphorous acidJournal of the American Chemical Society, 1988
- Novel activating and capping reagents for improved hydrogen-phosphonate DNA synthesisTetrahedron Letters, 1988
- Nucleoside H-phosphonates. III. Chemical synthesis of oligodeoxyribonucleotides by the hydrogenphosphonate approachTetrahedron Letters, 1986
- Deoxynucleoside H-Phosphonate diester intermediates in the synthesis of internucleotide phosphate analoguesTetrahedron Letters, 1986