Mitogenic Signaling of Insulin-like Growth Factor I in MCF-7 Human Breast Cancer Cells Requires Phosphatidylinositol 3-Kinase and Is Independent of Mitogen-activated Protein Kinase
Open Access
- 1 December 1997
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 272 (49), 31163-31171
- https://doi.org/10.1074/jbc.272.49.31163
Abstract
No abstract availableKeywords
This publication has 50 references indexed in Scilit:
- Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase PathwaysPublished by Elsevier BV ,1997
- The 70 kDa S6 Kinase Complexes with and Is Activated by the Rho Family G Proteins Cdc42 and Rac1Cell, 1996
- Inhibition of the Melanoma Cell Cycle and Regulation at the G1/S Transition by 12-O-Tetradecanoylphorbol-13-acetate (TPA) by Modulation of CDK2 ActivityExperimental Cell Research, 1995
- IL-1 Induces Expression of WAF1 mRNA in Human Fibroblasts: Mechanisms of AccumulationBiochemical and Biophysical Research Communications, 1995
- Role of Phosphatidylinositol-3-Kinase in Insulin Receptor Signaling: Studies with Inhibitor, LY294002Biochemical and Biophysical Research Communications, 1994
- Phosphatidylinositol-3-OH kinase direct target of RasNature, 1994
- The Function of GRB2 in Linking the Insulin Receptor to Ras Signaling PathwaysScience, 1993
- The effects of corticotrophin (ACTH1–24), cyclic AMP and TPA (12-0-tetradecanoyl phorbol-13-acetate) on DNA replication and proliferation of primary rabbit adrenocortical cells in a synthetic mediumBiochemical and Biophysical Research Communications, 1987
- Human insulin receptor and its relationship to the tyrosine kinase family of oncogenesNature, 1985
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976