Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation
- 29 January 1981
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 289 (5796), 373-378
- https://doi.org/10.1038/289373a0
Abstract
Four ‘antigenic sites’ on the three-dimensional structure of the influenza haemagglutinin are identified. At least one amino acid substitution in each site seems to be required for the production of new epidemic strains between 1968 and 1975.Keywords
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