Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
- 1 January 1981
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 289 (5796), 366-373
- https://doi.org/10.1038/289366a0
Abstract
The haemagglutinin glycoprotein of influenza virus is a trimer comprising two structurally distinct regions: a triple-stranded coiled-coil of α-helices extends 76 Å from the membrane and a globular region of antiparallel β-sheet, which contains the receptor binding site and the variable antigenic determinants, is positioned on top of this stem. Each subunit has an unusual loop-like topology, starting at the membrane, extending 135 Å distally and folding back to enter the membrane.This publication has 37 references indexed in Scilit:
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