Minimally invasive surgical technique and enamel matrix derivative in intra‐bony defects. I: clinical outcomes and morbidity
- 22 October 2007
- journal article
- Published by Wiley in Journal of Clinical Periodontology
- Vol. 34 (12), 1082-1088
- https://doi.org/10.1111/j.1600-051x.2007.01144.x
Abstract
This case cohort study was designed to evaluate the clinical performance and the intra-operative and post-operative morbidity of the minimally invasive surgical technique (MIST) associated with the application of an enamel matrix derivative (EMD) in the treatment of isolated deep intra-bony defects.Forty deep isolated intra-bony defects in 40 patients were surgically accessed with the MIST. This technique was designed to limit the mesio-distal flap extension and the corono-apical flap reflection in order to reduce the surgical trauma and increase flap stability. The incision of the defect-associated papilla was performed according to the principles of the papilla preservation techniques. EMD was applied on the debrided and dried root surfaces. Stable primary closure of the flaps was obtained with modified internal mattress sutures. Surgery was performed with the aid of an operating microscope and microsurgical instruments. Clinical outcomes were collected at baseline and at 1 year. Intra-operative and post-operative morbidity was evaluated with questionnaires.The 1-year clinical attachment gain was 4.9+/-1.7 mm (p<0.0001 compared with baseline). This corresponded to a 77.6+/-21.9% resolution of the defect. Residual probing pocket depths were 3+/-0.6 mm. A minimal increase of 0.4+/-0.7 mm in gingival recession between baseline and 1 year was recorded. No patients experienced intra-operative pain, while only 14 reported a very moderate perception of the hardship of the surgical procedure [7+/-12 visual-analogue scale (VAS) units, on average]. Primary closure was obtained in all treated sites. At the 1-week follow-up visit, 38 sites (95%) were still closed. Only 12 subjects reported moderate post-operative pain (VAS 19+/-10) that lasted for 26+/-17 h.These data indicate that the minimally invasive surgical technique, in combination with EMD, can be successfully applied in the treatment of isolated deep intra-bony defects, resulting in excellent clinical outcomes with very limited intra- and post-operative morbidity.Keywords
This publication has 23 references indexed in Scilit:
- A minimally invasive surgical technique with an enamel matrix derivative in the regenerative treatment of intra‐bony defects: a novel approach to limit morbidityJournal of Clinical Periodontology, 2006
- Clinical Performance of a Regenerative Strategy for Intrabony Defects: Scientific Evidence and Clinical ExperienceThe Journal of Periodontology, 2005
- Prospective Assessment of the Use of Enamel Matrix Proteins With Minimally Invasive SurgeryThe Journal of Periodontology, 2005
- Healing, post‐operative morbidity and patient perception of outcomes following regenerative therapy of deep intrabony defectsJournal of Clinical Periodontology, 2004
- Enamel matrix proteins in the regenerative therapy of deep intrabony defectsJournal of Clinical Periodontology, 2002
- Microsurgical Approach to Periodontal Regeneration. Initial Evaluation in a Case CohortThe Journal of Periodontology, 2001
- Effect of cigarette smoking on periodontal healing following GTR in infrabony defectsJournal of Clinical Periodontology, 1995
- The Plaque Control RecordThe Journal of Periodontology, 1972
- New Attachment of Periodontal Tissues After Treatment of Intrabony LesionsThe Journal of Periodontology, 1971
- Repair Following Mucoperiosteal Flap Surgery With Full Gingival RetentionThe Journal of Periodontology, 1968