Prospective Assessment of the Use of Enamel Matrix Proteins With Minimally Invasive Surgery
- 1 March 2005
- journal article
- Published by Wiley in The Journal of Periodontology
- Vol. 76 (3), 380-384
- https://doi.org/10.1902/jop.2005.76.3.380
Abstract
Minimally invasive surgery (MIS) is a surgical technique using very small incisions, indicated for performing regenerative therapy in periodontal defects. Enamel matrix proteins (EMP) have been shown to enhance periodontal regeneration. This study was undertaken to determine the effect of using EMP in combination with an MIS approach. Patients from two private periodontal practices with chronic periodontitis who, following non-surgical therapy, had one or more sites with probing depths (PD) of > or =6 mm were included in the study. An MIS approach was utilized for surgical access. Following surgical debridement, EMP was placed into the bony defect. The surgical sites were reevaluated after at least 11 months. Surgical treatment was performed at 160 sites in 16 patients. No significant differences were noted in the results between the two offices and the data were combined. Mean PD reduction (P = 0.002) and attachment level improvements (P = 0.012) were significantly greater than 3 mm with mean post-surgical PD of 3.17 mm and attachment levels of 4.05 mm, based on subject means. Mean change in recession following surgery was negligible (0.01 mm). All sites were considered to be clinically successful. The combination of MIS and EMP yields significant reductions in probing depths and improvements in attachment levels while producing little or no increase in recession.Keywords
This publication has 13 references indexed in Scilit:
- The Effect of Enamel Matrix Proteins on Periodontal Regeneration as Determined by Histological AnalysesThe Journal of Periodontology, 2003
- Histologic Evaluation of Human Intrabony Defects Following Non‐Surgical Periodontal Therapy With and Without Application of an Enamel Matrix Protein DerivativeThe Journal of Periodontology, 2003
- A Retrospective Case Series Comparing the Use of Demineralized Freeze-Dried Bone Allograft and Freeze-Dried Bone Allograft Combined With Enamel Matrix Derivative for the Treatment of Advanced Osseous LesionsThe Journal of Periodontology, 2002
- Enamel Matrix Proteins and Guided Tissue Regeneration With Titanium‐Reinforced Expanded PolytetrafluoroethyleneMembranes in the Treatment of Infrabony Defects: A Comparative Controlled Clinical TrialThe Journal of Periodontology, 2002
- Longitudinal Comparisons of the Periodontal Status of Patients with Moderate to Severe Periodontal Disease Receiving No Treatment, Non‐Surgical Treatment, and Surgical Treatment Utilizing Individual Sites for AnalysisThe Journal of Periodontology, 2001
- Microsurgical Approach to Periodontal Regeneration. Initial Evaluation in a Case CohortThe Journal of Periodontology, 2001
- Porcine Fetal Enamel Matrix Derivative Enhances Bone Formation Induced by Demineralized Freeze Dried Bone Allograft In VivoThe Journal of Periodontology, 2000
- A Minimally Invasive Surgical Approach for Periodontal Regeneration: Surgical Technique and ObservationsThe Journal of Periodontology, 1999
- Periodontal Regeneration Around Natural TeethAnnals of Periodontology, 1996
- Minimally invasive surgeryBritish Journal of Surgery, 1990