MHPG Excretion in Depressive Disorders: Relation to Clinical Subtypes and Desynchronized Sleep
- 24 August 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 181 (4101), 762-764
- https://doi.org/10.1126/science.181.4101.762
Abstract
The urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) was significantly lower in patients with manic-depressive depressions than in patients with chronic characterological depressions. There was an inverse relationship between MHPG excretion and the amount of time spent in desynchronized sleep, particularly in the manic-depressive disorders. Excretion of MHPG was not related to the degree of retardation, agitation, or anxiety in these patients.Keywords
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