Quantitative Electron Microscopic Autoradiography of Insulin, Glucagon, and Somatostatin Binding Sites on Islets
- 17 September 1982
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4565), 1155-1156
- https://doi.org/10.1126/science.6126003
Abstract
After monolayer cultures of rat islets were exposed to [125I]insulin,[125I]glucagon, and [125I]tyrosinyl somatostatin, specific autoradiographic grains associated with each radioactively labeled ligand were found on B, A, and D cells.The density of labeling of the B, A, and D cells with each labeled ligand correlated well with the known actions of the three hormones on each of the islet cells.This publication has 19 references indexed in Scilit:
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