Recent Trends in the Prevalence of Crohn’s Disease and Ulcerative Colitis in a Commercially Insured US Population
Open Access
- 29 August 2012
- journal article
- research article
- Published by Springer Science and Business Media LLC in Digestive Diseases and Sciences
- Vol. 58 (2), 519-525
- https://doi.org/10.1007/s10620-012-2371-5
Abstract
Purpose Most US inflammatory bowel disease (IBD) epidemiology studies conducted to date have sampled small, geographically restricted populations and have not examined time trends. The aim of our study was to determine the prevalence of Crohn’s disease (CD) and ulcerative colitis (UC) in a commercially insured US population and compare prevalences across sociodemographic characteristics and time. Methods Using claims data from approximately 12 million Americans, we performed three consecutive 2-year cross-sectional studies. Cases of CD and UC were identified using a previously described algorithm. Prevalence was estimated by dividing cases by individuals in the source population. Logistic regression was used to compare prevalences by region, age, and sex. Results In 2009, the prevalences of CD and UC in children were 58 [95 % confidence interval (CI) 55–60] and 34 (95 % CI 32–36), respectively. In adults, the respective prevalences were 241 (95 % CI 238–245) and 263 (95 % CI 260–266). Data analysis revealed that IBD prevalences have slightly increased over time. Based on census data, an estimated 1,171,000 Americans have IBD (565,000 CD and 593,000 UC). Conclusions Analysis of the epidemiological data revealed an increasing burden of IBD in recent years, which may be used to inform policy.This publication has 13 references indexed in Scilit:
- Utilization of healthcare resources by U.S. children and adults with inflammatory bowel diseaseInflammatory Bowel Diseases, 2011
- Effects of fistula on healthcare costs and utilization for patients with Crohnʼs disease treated in a managed care environmentInflammatory Bowel Diseases, 2008
- Incidence and Prevalence of Inflammatory Bowel Disease in a Northern California Managed Care Organization, 1996-2002The American Journal of Gastroenterology, 2008
- The Prevalence and Geographic Distribution of Crohn’s Disease and Ulcerative Colitis in the United StatesClinical Gastroenterology and Hepatology, 2007
- Estimation of the Period Prevalence of Inflammatory Bowel Disease Among Nine Health Plans Using Computerized Diagnoses and Outpatient Pharmacy DispensingsInflammatory Bowel Diseases, 2007
- Infliximab Drug and Infusion Costs Among Patients With Crohn's Disease in a Commercially-Insured SettingClinical Journal of Sport Medicine, 2006
- The Epidemiology of Inflammatory Bowel Disease in Canada: A Population-Based StudyThe American Journal of Gastroenterology, 2006
- Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in wisconsin: a statewide population-based studyThe Journal of Pediatrics, 2003
- Comparison of asthma costs in patients starting fluticasone propionate compared to patients starting montelukastRespiratory Medicine, 2001
- Epidemiology of Crohn's Disease and Ulcerative Colitis in a Central Canadian Province: A Population-based StudyAmerican Journal of Epidemiology, 1999