Synthesis and characterization of selective dopamine D2 receptor ligands using aripiprazole as the lead compound
- 1 June 2011
- journal article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry
- Vol. 19 (11), 3502-3511
- https://doi.org/10.1016/j.bmc.2011.04.021
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Effect of cyclosporin A on the uptake of D3-selective PET radiotracers in rat brainNuclear Medicine and Biology, 2011
- Endogenous dopamine (DA) competes with the binding of a radiolabeled D3 receptor partial agonist in vivo: A positron emission tomography studySynapse, 2010
- Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626Bioorganic & Medicinal Chemistry, 2010
- Positron emission tomography imaging of dopamine D2/3 receptors in the human cortex with [11C]FLB 457: Reproducibility studiesSynapse, 2010
- [3H]4-(dimethylamino)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl) butyl)benzamide: A selective radioligand for dopamine D3receptors. II. Quantitative analysis of dopamine D3and D2receptor density ratio in the caudate-putamenSynapse, 2010
- [3H]4‐(Dimethylamino)‐N‐[4‐(4‐(2‐methoxyphenyl)piperazin‐ 1‐yl)butyl]benzamide, a selective radioligand for dopamine D3 receptors. I. In vitro characterizationSynapse, 2009
- Rat liver and kidney contain high densities of σ1 and σ2 receptors: characterization by ligand binding and photoaffinity labelingEuropean Journal of Pharmacology: Molecular Pharmacology, 1994
- Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neurolepticsNature, 1990
- Studies on 2(1H)-quinolinone derivatives as neuroleptic agents. I. Synthesis and biological activities of (4-phenyl-1-piperazinyl)-propoxy-2(1H)-quinolinone derivatives.CHEMICAL & PHARMACEUTICAL BULLETIN, 1988
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973