Smads 2 and 3 Are Differentially Activated by Transforming Growth Factor-β (TGF-β) in Quiescent and Activated Hepatic Stellate Cells
Open Access
- 1 March 2003
- journal article
- Published by Elsevier BV
- Vol. 278 (13), 11721-11728
- https://doi.org/10.1074/jbc.m207728200
Abstract
No abstract availableKeywords
This publication has 67 references indexed in Scilit:
- Expression of Smads during in Vitro Transdifferentiation of Hepatic Stellate Cells to MyofibroblastsBiochemical and Biophysical Research Communications, 2001
- Interaction between Smad Anchor for Receptor Activation and Smad3 Is Not Essential for TGF-β/Smad3-Mediated SignalingBiochemical and Biophysical Research Communications, 2001
- Two Divergent Signaling Pathways for TGF-β Separated by a Mutation of Its Type II Receptor GeneBiochemical and Biophysical Research Communications, 1999
- Role of transforming growth factor ? type II receptor in hepatic fibrosis: Studies of human chronic hepatitis C and experimental fibrosis in ratsHepatology, 1999
- The role of TGFβ1 in initiating hepatic stellate cell activation in vivoJournal of Hepatology, 1999
- Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-α and TGF-β1Journal of Hepatology, 1999
- Localization and cellular sources of activins in normal and fibrotic rat liverHepatology, 1997
- Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cellsProceedings of the National Academy of Sciences of the United States of America, 1997
- Tumor necrosis factor alpha (TNFα) and transforming growth factor β1 (TGFβ1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblastsVirchows Archiv B Cell Pathology Including Molecular Pathology, 1993
- Metabolism and effects on biliary lipid secretion of murocholic acid in the hamsterJournal of Hepatology, 1990