Hypoglycemic effect of aqueous extract ofParthenium hysterophorusL. in normal and alloxan induced diabetic rats
Open Access
- 1 January 2008
- journal article
- research article
- Published by Medknow in Indian Journal of Pharmacology
- Vol. 40 (4), 183-185
- https://doi.org/10.4103/0253-7613.43167
Abstract
Objectives: To study the effects of Parthenium hysterophorus L. flower on serum glucose level in normal and alloxan induced diabetic rats. Materials and Methods: Albino rats were divided into six groups of six animals each, three groups of normal animals receiving different treatments consisting of vehicle, aqueous extract of Parthenium hysterophorus L. flower (100 mg/kg) and the standard antidiabetic drug, glibenclamide (0.5 mg/kg). The same treatment was given to the other three groups comprising alloxan induced diabetic animals. Fasting blood glucose level was estimated using the glucose oxidase method in normal and alloxan induced diabetic rats, before and 2 h after the administration of drugs. Results: Parthenium hysterophorus L. showed significant reduction in blood glucose level in the diabetic (P Parthenium hysterophorus L. flower extract is very promising for developing standardized phytomedicine for diabetes mellitus.Keywords
This publication has 5 references indexed in Scilit:
- A Controlled Evaluation of Staging Dietary Patterns to Reduce the Risk of Diabetes in African-American WomenDiabetes Care, 2002
- Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production.Journal of Clinical Endocrinology & Metabolism, 1996
- Effect of D-400, a herbal formulation, on blood sugar of normal and alloxan-induced diabetic rats.1995
- An improved colour reagent for the determination of blood glucose by the oxidase systemThe Analyst, 1972
- Recent research in indigenous anti-diabetic medicinal plants--an over-all assessment.1970