Antiprotozoal Activity of the Constituents of Conyza filaginoides
- 1 May 2001
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 64 (5), 671-673
- https://doi.org/10.1021/np000442o
Abstract
Bioassay-guided fractionation of the antiprotozoal extract of Conyza filaginoides led to the isolation of three new flavonol caffeoyl glycosides, namely, kaempferol 3-O-(6‘ ‘-O-E-caffeoyl)-β-d-galactopyranoside (1), isorhamnetin 3-O-(6‘ ‘-O-E-caffeoyl)-β-d-galactopyranoside (2), and quercetin 3-O-(6‘ ‘-O-E-caffeoyl)-β-d-glucopyranoside (3). In addition, seven known compounds, erythrodiol (4), β-caryophyllene-4,5-α-oxide (5), astragalin (6), isoquercitrin (7), nicotiflorin (8), narcissin (9), and rutin (10), were obtained. The structures of the new isolates were elucidated by spectroscopic and chemical methods. Compounds were also assessed for antiamoebic and antigiardial activities, but none was significantly active compared to the standard drugs evaluated.Keywords
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