Surveillance of HCC Patients after Liver RFA: Role of MRI with Hepatospecific Contrast versus Three-Phase CT Scan—Experience of High Volume Oncologic Institute
Open Access
- 12 November 2013
- journal article
- research article
- Published by Hindawi Limited in Gastroenterology Research and Practice
- Vol. 2013, 1-9
- https://doi.org/10.1155/2013/469097
Abstract
Purpose. To compare the diagnostic accuracy of hepatospecific contrast-enhanced MRI versus triple-phase CT scan after radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients.Methods. Thirty-four consecutive HCC patients (42 hepatic nodules) were treated with percutaneous RFA and underwent MR and CT scans. All patients were enrolled in a research protocol that included CT with iodized contrast medium injection and MR with hepatospecific contrast medium injection. All patients were restaged within four weeks and at 3 months from ablation. The images were reviewed by four different radiologists to evaluate tumor necrosis, residual or recurrence disease, and evidence of new foci.Results. Thirty-two nodules were necrotic after treatment; 10 showed residual disease. Six new HCCs were identified. At first month followup CT has identified 34 necrotic lesions and 8 residual diseases; no new foci were recognized. At MRI instead, 32 complete necrotic lesions were identified, 10 lesions showed residual disease, and 2 new HCCs were found. At three months, CT demonstrated 33 completely necrotic lesions, 9 residual diseases, and 2 new HCCs. MR showed 31 complete necrotic lesions, 11 cases of residual disease, and 6 new HCCs.Conclusions. Hepatospecific contrast-enhanced MRI is more effective than multiphase CT in assessment of HCC treated with RFA.Keywords
This publication has 23 references indexed in Scilit:
- Is Gadoxetate Disodium–Enhanced MRI Useful for Detecting Local Recurrence of Hepatocellular Carcinoma After Radiofrequency Ablation Therapy?American Journal of Roentgenology, 2012
- Comparison of Milan and UCSF criteria for liver transplantation to treat hepatocellular carcinomaWorld Journal of Gastroenterology, 2011
- Magnetic Resonance Imaging of Radiofrequency Current-Induced Coagulation Zones in the Ex Vivo Bovine LiverRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 2010
- Thermoablative Treatments for Malignant Liver Lesions: 10-Year Experience of MRI Appearances of Treatment ResponseAmerican Journal of Roentgenology, 2010
- Evaluation of tumor response after locoregional therapies in hepatocellular carcinomaCancer, 2009
- Management of hepatocellular carcinomaHepatology, 2005
- Characterization of small nodules in cirrhosis by assessment of vascularity: The problem of hypovascular hepatocellular carcinomaHepatology, 2005
- ROC AnalysisAmerican Journal of Roentgenology, 2005
- Early and Late Complications After Radiofrequency Ablation of Malignant Liver Tumors in 608 PatientsAnnals of Surgery, 2004
- New Guidelines to Evaluate the Response to Treatment in Solid TumorsJNCI Journal of the National Cancer Institute, 2000