Tacrolimus leukoencephalopathy: A neuropathologic confirmation
- 28 September 2004
- journal article
- case report
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 63 (6), 1132-1133
- https://doi.org/10.1212/01.wnl.0000138568.60774.e4
Abstract
A 40-year-old woman with biopsy-proven acute rejection was admitted 3 weeks after an orthotopic liver transplant for alcoholic cirrhosis. Alanine aminotransferase was elevated at 226 IU/L (<50 IU/L). She also had elevated cholesterol levels (237–411 IU/L) and was hypertensive (approximately 160/90). Erythrocytes showed anisocytosis and poikilocytosis (spiculated, fragmented, and targets). Tacrolimus 4 mg BID had been started the day after transplantation.Keywords
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