An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
- 13 February 2006
- journal article
- letter
- Published by Springer Science and Business Media LLC in Nature Chemical Biology
- Vol. 2 (4), 202-206
- https://doi.org/10.1038/nchembio774
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- Activation of the DNA damage checkpoint and genomic instability in human precancerous lesionsNature, 2005
- Genetic and Genomic Approaches to Identify and Study the Targets of Bioactive Small MoleculesCell Chemical Biology, 2004
- A large-scale RNAi screen in human cells identifies new components of the p53 pathwayNature, 2004
- In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2Science, 2004
- Turning the key on p53Nature, 2004
- New tools for functional mammalian cancer geneticsNature Reviews Cancer, 2003
- 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancerNature, 2002
- Surfing the p53 networkNature, 2000
- Regulation of p53 stability by Mdm2Nature, 1997
- Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation DomainScience, 1996