Factors Characterizing Staphylococcus epidermidis Invasiveness Determined by Comparative Genomics
Open Access
- 1 March 2005
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 73 (3), 1856-1860
- https://doi.org/10.1128/iai.73.3.1856-1860.2005
Abstract
Virulence mechanisms of the leading nosocomial pathogen Staphylococcus epidermidis are poorly understood. We used microarray-based genome-wide comparison of clinical and commensal S. epidermidis strains to identify putative virulence determinants. Our study revealed high genetic variability of the S. epidermidis genome, new markers for invasiveness of S. epidermidis , and potential targets for drug development against S. epidermidis infections.Keywords
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