The Effect of Fig Tree Latex (Ficus carica) on Stomach Cancer Line
Open Access
- 1 April 2011
- journal article
- Vol. 13 (4), 272-275
Abstract
The therapeutic effect of herbal materials in inhibition of cancer cell growth was shown. This study investigates the effect of fig tree latex (Ficus carica) on stomach cancer line. The in vitro effect of different doses of fig tree latex on stomach cancer cell line and the peripheral blood mononuclear cells was evaluated after 72 hours. Fig tree latex could inhibit the proliferation of cancer cell line without any cytotoxic effect on human normal cells. Five mg/ml was the optimum concentration in inhibition of cell line growth. Cancer cell line was more sensitive to Ficus carica latex than normal cells. This anticancer activity might be due to presence of its proteolytic enzymes.Keywords
This publication has 19 references indexed in Scilit:
- Factors associated with cancer-related fatigue in breast cancer patients undergoing endocrine therapy in an urban setting: a cross-sectional studyBMC Cancer, 2010
- Microarray: an instrument for cancer surgeons of the future?Anz Journal of Surgery, 2010
- Purification, Characterization, and Solvent-Induced Thermal Stabilization of Ficin from Ficus caricaJournal of Agricultural and Food Chemistry, 2008
- Emerging roles of proteases in tumour suppressionNature Reviews Cancer, 2007
- Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cellsCancer Letters, 2005
- A census of human cancer genesNature Reviews Cancer, 2004
- Natural products in cancer chemotherapy: past, present and futureNature Reviews Cancer, 2002
- Suppressors of Cancer Cell Proliferation from Fig (Ficus carica) Resin: Isolation and Structure ElucidationJournal of Natural Products, 2001
- Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancerJCI Insight, 2001
- Cancer prevention: epidemiology and experimentCancer Letters, 1997