Peptidoglycan structure and architecture
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Open Access
- 11 February 2008
- journal article
- review article
- Published by Oxford University Press (OUP) in FEMS Microbiology Reviews
- Vol. 32 (2), 149-167
- https://doi.org/10.1111/j.1574-6976.2007.00094.x
Abstract
The peptidoglycan (murein) sacculus is a unique and essential structural element in the cell wall of most bacteria. Made of glycan strands cross-linked by short peptides, the sacculus forms a closed, bag-shaped structure surrounding the cytoplasmic membrane. There is a high diversity in the composition and sequence of the peptides in the peptidoglycan from different species. Furthermore, in several species examined, the fine structure of the peptidoglycan significantly varies with the growth conditions. Limited number of biophysical data on the thickness, elasticity and porosity of peptidoglycan are available. The different models for the architecture of peptidoglycan are discussed with respect to structural and physical parameters.Keywords
This publication has 118 references indexed in Scilit:
- The penicillin-binding proteins: structure and role in peptidoglycan biosynthesisFEMS Microbiology Reviews, 2008
- Idiosyncratic features in tRNAs participating in bacterial cell wall synthesisNucleic Acids Research, 2007
- Identification of the l , d -Transpeptidases Responsible for Attachment of the Braun Lipoprotein to Escherichia coli PeptidoglycanJournal of Bacteriology, 2007
- Protein mobility and diffusive barriers in Escherichia coli: consequences of osmotic stressMolecular Microbiology, 2007
- A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune systemProceedings of the National Academy of Sciences of the United States of America, 2007
- Characterization of Helicobacter pylori Lytic Transglycosylases Slt and MltDJournal of Bacteriology, 2007
- Granular Layer in the Periplasmic Space of Gram-Positive Bacteria and Fine Structures ofEnterococcus gallinarumandStreptococcus gordoniiSepta Revealed by Cryo-Electron Microscopy of Vitreous SectionsJournal of Bacteriology, 2006
- Genes for the peptidoglycan synthesis pathway are essential for chloroplast division in mossProceedings of the National Academy of Sciences of the United States of America, 2006
- Length Distribution of the Peptidoglycan Chains in the Sacculus of Escherichia coliJournal of Theoretical Biology, 2000
- Alterations of murein structure and of penicillin-binding proteins in minicells from Escherichia coliMicrobiology, 1994