Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection
- 1 November 1992
- journal article
- review article
- Published by Elsevier BV in Trends in Genetics
- Vol. 8 (11), 387-391
- https://doi.org/10.1016/0168-9525(92)90300-s
Abstract
Genetic studies of many diversely regulated genes in the yeast Saccharomyces cerevisiae have identified two groups of genes with global functions in transcription. The first group comprises five SNF and SWI genes required for transcriptional activation. The other group, containing SPT and SIN genes, was identified by suppressor analysis and includes genes that encode histones. Recent evidence suggests that these SNF/SWI and SPT/SIN genes control transcription via effects on chromatin. SNF2/SWI2 sequence homologues have been identified in many organisms, suggesting that the SNF/SWI and SPT/SIN functions are conserved throughout eukaryotes.Keywords
This publication has 35 references indexed in Scilit:
- Chromatin as an essential part of the transcriptional mechanimNature, 1992
- Irresistible force meets immovable object: Transcription and the nucleosomeCell, 1991
- Nucleosomes: regulators of transcriptionTrends in Genetics, 1990
- SNF6 encodes a nuclear protein that is required for expression of many genes in Saccharomyces cerevisiae.Molecular and Cellular Biology, 1990
- RNA POLYMERASE B (II) AND GENERAL TRANSCRIPTION FACTORSAnnual Review of Biochemistry, 1990
- Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulatorsCell, 1987
- Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeastCell, 1987
- Activation of the yeast HO gene by release from multiple negative controlsCell, 1987
- Five SWI genes are required for expression of the HO gene in yeastJournal of Molecular Biology, 1984
- Molecular analysis of a cell lineageNature, 1983