Differentiation and Quantitative Determination of Surface and Hydrate Water in Lyophilized Mannitol Using NIR Spectroscopy
- 30 September 2006
- journal article
- Published by Elsevier BV in Journal of Pharmaceutical Sciences
- Vol. 95 (9), 2077-2086
- https://doi.org/10.1002/jps.20706
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Characterization and Crystal Structure of D‐Mannitol HemihydrateJournal of Pharmaceutical Sciences, 2004
- Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride.Pharmaceutical Research, 2003
- Crystallization behavior of mannitol in frozen aqueous solutions.Pharmaceutical Research, 2002
- Hydrate Formation During Wet Granulation Studied by Spectroscopic Methods and Multivariate AnalysisPharmaceutical Research, 2002
- Energy/Temperature Diagram and Compression Behavior of the Polymorphs of d-MannitolJournal of Pharmaceutical Sciences, 2000
- Existence of a mannitol hydrate during freeze‐drying and practical implicationsJournal of Pharmaceutical Sciences, 1999
- The Physical State of Mannitol after Freeze-Drying: Effects of Mannitol Concentration, Freezing Rate, and a Noncrystallizing CosoluteJournal of Pharmaceutical Sciences, 1998
- The use of near-infrared spectroscopy in the efficient prediction of a specification for the residual moisture content of a freeze-dried productJournal of Pharmaceutical and Biomedical Analysis, 1998
- Near-Infrared Spectroscopic Determination of Residual Moisture in Lyophilized Sucrose Through Intact Glass VialsPharmaceutical Research, 1989
- The mechanism of cryoprotection of proteins by solutesCryobiology, 1988