Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase)
- 29 February 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 229 (1), 206-210
- https://doi.org/10.1016/0014-5793(88)80828-7
Abstract
We have isolated a cDNA clone encoding human enkephalinase (neutral endopeptidase, EC 3.4.24.11) in a λgt10 library from human placenta, and present the complete 742 amino acid sequence of human enkephalinase. The human enzyme displays a high homology with rat and rabbit enkephalinase. Like the rat and rabbit enzyme, human enkephalinase contains a single N-terminal transmembrane region and is likely to be inserted through cell membranes with the majority of protein, including its carboxy-terminus, located extracellularly.This publication has 17 references indexed in Scilit:
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