Clinical patterns of cutaneous nontuberculous mycobacterial infections
- 11 April 2005
- journal article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 152 (4), 727-734
- https://doi.org/10.1111/j.1365-2133.2005.06519.x
Abstract
Background Cutaneous nontuberculous mycobacterial infections result from external inoculation, spread of a deeper infection, or haematogenous spread of a disseminated infection. There are two species-specific infections (fish-tank or swimming-pool granuloma, due to Mycobacterium marinum, and Buruli ulcer, caused by M. ulcerans). Most infections, however, produce a nonspecific clinical picture. Objectives To define clinical patterns of cutaneous disease in nontuberculous mycobacterial infections. Methods Fifty-one patients with cutaneous nontuberculous mycobacterial infections were reviewed. Clinical and histopathological features of normal hosts and immunosuppressed patients were compared. Two subgroups of immunosuppressed patients were distinguished: patients with cutaneous infection and patients with a disseminated infection and cutaneous involvement. Results In immunosuppressed patients the number of lesions was significantly higher. Abscesses and ulceration were also more frequently observed. Different species were found in normal hosts and immunosuppressed patients. Several clinical patterns of cutaneous infection were defined: lymphocutaneous or sporotrichoid lesions; nonlymphocutaneous lesions at the site of trauma; folliculitis and furunculosis involving the lower extremities; disseminated lesions on the extremities in immunosuppressed patients. Two patterns were observed in patients with a disseminated infection: localized cutaneous lesions and disseminated cutaneous and mucosal lesions. Conclusions Cutaneous manifestations of nontuberculous mycobacterial infections may be classified according to criteria such as cutaneous lesions and immune status.Keywords
This publication has 33 references indexed in Scilit:
- Mycobacterium abscessus cellulitis and multifocal abscesses of the breasts in a transsexual from illicit intramammary injections of siliconeJournal of the American Academy of Dermatology, 2004
- Buruli Ulcer: A Systemic DiseaseClinical Infectious Diseases, 2003
- The Hospital Water Supply as a Source of Nosocomial InfectionsArchives of Internal Medicine, 2002
- Hautknoten und Ulzera der Extremitäten bei einem Patienten mit rheumatoider ArthritisDeutsche Medizinische Wochenschrift (1946), 2002
- Foliculitis postdepilación por Mycobacterium chelonaeActas Dermo-Sifiliograficas, 2002
- Cutaneous infections due to nontuberculous mycobacteria: histopathological review of 28 cases. Comparative study between lesions observed in immunosuppressed patients and normal hostsJournal of Cutaneous Pathology, 2000
- Diagnosis and Treatment of Disease Caused by Nontuberculous MycobacteriaAmerican Journal of Respiratory and Critical Care Medicine, 1997
- Disseminated Osteomyelitis from Mycobacterium ulcerans after a SnakebiteThe New England Journal of Medicine, 1993
- Disseminated Infection with Rapidly Growing MycobacteriaClinical Infectious Diseases, 1993
- Spectrum of Disease Due to Rapidly Growing MycobacteriaClinical Infectious Diseases, 1983