One-dimensional deterministic transport in neurons measured by dispersion-relation phase spectroscopy
Open Access
- 23 August 2011
- journal article
- Published by IOP Publishing in Journal of Physics: Condensed Matter
- Vol. 23 (37), 374107
- https://doi.org/10.1088/0953-8984/23/37/374107
Abstract
We studied the active transport of intracellular components along neuron processes using a new method developed in our laboratory: dispersion-relation phase spectroscopy. This method is able to quantitatively map spatially the heterogeneous dynamics of the concentration field of the cargos at submicron resolution without the need for tracking individual components. The results in terms of density correlation function reveal that the decay rate is linear in wavenumber, which is consistent with a narrow Lorentzian distribution of cargo velocity.Keywords
This publication has 51 references indexed in Scilit:
- Measurement of red blood cell mechanics during morphological changesProceedings of the National Academy of Sciences of the United States of America, 2010
- Metabolic remodeling of the human red blood cell membraneProceedings of the National Academy of Sciences of the United States of America, 2010
- Anomalous yet BrownianProceedings of the National Academy of Sciences of the United States of America, 2009
- Intracellular transport by active diffusionTrends in Cell Biology, 2009
- Cytoplasmic diffusion: molecular motors mix it upThe Journal of cell biology, 2008
- Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparumProceedings of the National Academy of Sciences of the United States of America, 2008
- Optical imaging of cell mass and growth dynamicsAmerican Journal of Physiology-Cell Physiology, 2008
- Universal physical responses to stretch in the living cellNature, 2007
- Design and validation of a tool for neurite tracing and analysis in fluorescence microscopy imagesCytometry Part A, 2004
- Myosin V Walks Hand-Over-Hand: Single Fluorophore Imaging with 1.5-nm LocalizationScience, 2003