Regional adiposity distribution and insulin resistance in young Chinese and European Australian women
- 30 August 2011
- journal article
- Published by Taylor & Francis Ltd in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 71 (8), 653-657
- https://doi.org/10.3109/00365513.2011.618845
Abstract
Lower than normal leg fat mass and excessive trunk fat mass are predictive of insulin resistance (IR) in obese women of European descent. Whether this regional adiposity relationship applies to moderately overweight women of Chinese descent is undetermined. Thus, the relationship between leg and trunk fat mass and IR of young (22.3 ± 0.3 years) sedentary Australian women of either Chinese (CW; n = 22) or European (EW; n = 36) descent was examined. Subjects underwent a maximal oxygen uptake test, blood draw, and dual energy x-ray absorptiometry to measure body composition. Fasting insulin levels and C-reactive protein (CRP) were assessed by ELISA and IR was calculated by HOMA-IR. Blood lipids and glucose were quantified by an automated enzymatic method (Cholestech LDX, USA). Total, arm, trunk, and leg fat was significantly greater (p < 0.05) for the EW group, whereas IR was significantly higher for CW. Fasting lipids and glucose were within normal levels for both groups, whereas CRP levels were significantly higher in EW. For EW trunk fat mass was the only variable significantly correlated with IR (r = 0.40, p < 0.05). In contrast, for CW leg fat mass was significantly correlated with IR (r = − 0.49, p < 0.05). Greater trunk fat mass was associated with higher IR of Australian women of European descent, whereas smaller leg fat mass was associated with higher IR of women of Chinese descent.Keywords
This publication has 33 references indexed in Scilit:
- The Metabolic Syndrome and Cardiovascular Risk: A Systematic Review and Meta-AnalysisJournal of the American College of Cardiology, 2010
- Metabolic syndrome and risk of incident diabetes: findings from the European Prospective Investigation into Cancer and Nutrition-Potsdam StudyCardiovascular Diabetology, 2008
- Is insulin resistance the cause of the metabolic syndrome?Annals of Medicine, 2006
- Metabolic and Vascular Abnormalities in Subjects at Risk for Type 2 Diabetes: The Early Start of a Dangerous SituationArchives of Medical Research, 2005
- Relative risks of the metabolic syndrome according to the degree of insulin resistance in apparently healthy Korean adultsClinical Science, 2005
- Prevalence of the Metabolic Syndrome and Its Relation to All-Cause and Cardiovascular Mortality in Nondiabetic European Men and WomenArchives of Internal Medicine, 2004
- Can We Apply the National Cholesterol Education Program Adult Treatment Panel Definition of the Metabolic Syndrome to Asians?Diabetes Care, 2004
- Independent and opposite associations of waist and hip circumferences with diabetes, hypertension and dyslipidemia: the AusDiab StudyInternational Journal of Obesity, 2004
- Adipose tissue as a buffer for daily lipid fluxDiabetologia, 2002
- Body mass index, waist circumference, waist-hip ratio, and glucose intolerance in Chinese and Europid adults in Newcastle, UK.Journal of Epidemiology and Community Health, 1997