Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology
Top Cited Papers
Open Access
- 1 January 2013
- journal article
- review article
- Published by Hindawi Limited in Evidence-Based Complementary and Alternative Medicine
- Vol. 2013, 1-51
- https://doi.org/10.1155/2013/340215
Abstract
There are 230 to 240 knownBidensspecies. Among them,Bidens pilosais a representative perennial herb, globally distributed across temperate and tropical regions.B. pilosahas been traditionally used in foods and medicines without obvious adverse effects. Despite significant progress in phytochemical and biological analyses ofB. pilosaover the past few years, comprehensive and critical reviews of this plant are anachronistic or relatively limited in scope. The present review aims to summarize up-to-date information on the phytochemistry, pharmacology, and toxicology ofB. pilosafrom the literature. In addition to botanical studies and records of the traditional use ofB. pilosain over 40 diseases, scientific studies investigating the potential medicinal uses of this species and its constituent phytochemicals for a variety of disorders are presented and discussed. The structure, bioactivity, and likely mechanisms of action ofB. pilosaand its phytochemicals are emphasized. Although some progress has been made, further rigorous efforts are required to investigate the individual compounds isolated fromB. pilosato understand and validate its traditional uses and develop clinical applications. The present review provides preliminary information and gives guidance for further basic and clinical research into this plant.Keywords
Funding Information
- Academia Sinica (99-CDA-L11, 101S0010056)
This publication has 106 references indexed in Scilit:
- Antidiabetic Effect and Mode of Action of CytopiloyneEvidence-Based Complementary and Alternative Medicine, 2013
- Anti-carcinogenic Effects of the Flavonoid LuteolinMolecules, 2008
- Clinical and biochemical effects of a combination botanical product (ClearGuard™) for allergy: a pilot randomized double-blind placebo-controlled trialNutrition Journal, 2008
- Chemical composition and antioxidant, antibacterial and antifungal activities of the essential oils from Bidens pilosa Linn. var. RadiataFood Control, 2008
- The effect of centaurein on interferon-γ expression and Listeria infection in miceToxicology and Applied Pharmacology, 2007
- Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K–Akt pathwaysChemico-Biological Interactions, 2006
- Relaxant effects of the neutral extract of the leaves ofBidens pilosa Linn on isolated rat vascular smooth musclePhytotherapy Research, 2005
- Antihyperglycemic Acetylenic Glucosides fromBidens pilosaPlanta Medica, 2000
- Flavonoids from Bidens pilosa var. radiataPhytochemistry, 1997
- New aurone glucosides and new phenylpropanoid glucosides from Bidens pilosa.CHEMICAL & PHARMACEUTICAL BULLETIN, 1991