Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report
Open Access
- 1 August 2016
- journal article
- review article
- Published by American Thoracic Society in American Journal of Respiratory and Critical Care Medicine
- Vol. 194 (3), 265-275
- https://doi.org/10.1164/rccm.201604-0801ci
Abstract
Acute exacerbation of idiopathic pulmonary fibrosis has been defined as an acute, clinically significant, respiratory deterioration of unidentifiable cause. The objective of this international working group report on acute exacerbation of idiopathic pulmonary fibrosis was to provide a comprehensive update on the topic. A literature review was conducted to identify all relevant English text publications and abstracts. Evidence-based updates on the epidemiology, etiology, risk factors, prognosis, and management of acute exacerbations of idiopathic pulmonary fibrosis are provided. Finally, to better reflect the current state of knowledge and improve the feasibility of future research into its etiology and treatment, the working group proposes a new conceptual framework for acute respiratory deterioration in idiopathic pulmonary fibrosis and a revised definition and diagnostic criteria for acute exacerbation of idiopathic pulmonary fibrosis.Keywords
This publication has 87 references indexed in Scilit:
- Acute exacerbation of idiopathic pulmonary fibrosis: shifting the paradigmEuropean Respiratory Journal, 2015
- Macrophage Activation in Acute Exacerbation of Idiopathic Pulmonary FibrosisPLOS ONE, 2015
- Baseline KL-6 predicts increased risk for acute exacerbation of idiopathic pulmonary fibrosisRespiratory Medicine, 2014
- Outcomes in idiopathic pulmonary fibrosis: A meta-analysis from placebo controlled trialsRespiratory Medicine, 2013
- Acute exacerbation of idiopathic pulmonary fibrosis associated with air pollution exposureEuropean Respiratory Journal, 2013
- Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trialsRespiratory Research, 2013
- Predicting survival in newly diagnosed idiopathic pulmonary fibrosis: a 3-year prospective studyEuropean Respiratory Journal, 2012
- An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and ManagementAmerican Journal of Respiratory and Critical Care Medicine, 2011
- Acute Exacerbations of Idiopathic Pulmonary FibrosisAmerican Journal of Respiratory and Critical Care Medicine, 2007
- Acute exacerbation of idiopathic pulmonary fibrosis: frequency and clinical featuresEuropean Respiratory Journal, 2006