Coronary microvascular resistance: methods for its quantification in humans
Open Access
- 26 May 2009
- journal article
- review article
- Published by Springer Science and Business Media LLC in Basic Research in Cardiology
- Vol. 104 (5), 485-498
- https://doi.org/10.1007/s00395-009-0037-z
Abstract
Coronary microvascular dysfunction is a topic that has recently gained considerable interest in the medical community owing to the growing awareness that microvascular dysfunction occurs in a number of myocardial disease states and has important prognostic implications. With this growing awareness, comes the desire to accurately assess the functional capacity of the coronary microcirculation for diagnostic purposes as well as to monitor the effects of therapeutic interventions that are targeted at reversing the extent of coronary microvascular dysfunction. Measurements of coronary microvascular resistance play a pivotal role in achieving that goal and several invasive and noninvasive methods have been developed for its quantification. This review is intended to provide an update pertaining to the methodology of these different imaging techniques, including the discussion of their strengths and weaknesses.Keywords
This publication has 117 references indexed in Scilit:
- k-Space and Time Sensitivity Encoding–accelerated Myocardial Perfusion MR Imaging at 3.0 T: Comparison with 1.5 TRadiology, 2008
- High spatial resolution myocardial perfusion cardiac magnetic resonance for the detection of coronary artery diseaseEuropean Heart Journal, 2008
- Fast mapping of myocardial blood flow with MR first‐pass perfusion imagingMagnetic Resonance in Medicine, 2008
- Model prediction of subendocardial perfusion of the coronary circulation in the presence of an epicardial coronary artery stenosisMedical & Biological Engineering & Computing, 2008
- Role of PET in the evaluation and understanding of coronary physiologyJournal of Nuclear Cardiology, 2007
- Physiological Basis of Clinically Used Coronary Hemodynamic IndicesCirculation, 2006
- Hyperemic Stenosis Resistance Index for Evaluation of Functional Coronary Lesion SeverityCirculation, 2002
- N-13 ammonia as an indicator of myocardial blood flow.Circulation, 1981
- Coronary sinus reflux. A source of error in the measurement of thermodilution coronary sinus flow.Circulation, 1978
- Measurement of Coronary Sinus Blood Flow by Continuous Thermodilution in ManCirculation, 1971