Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles
- 25 September 2009
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 44,p. 6753-6755
- https://doi.org/10.1039/b915257a
Abstract
Quinidine derivative (QD)2PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity.Keywords
This publication has 88 references indexed in Scilit:
- Oxindole Synthesis by Direct Coupling of C-H and C-H CentersAngewandte Chemie-International Edition, 2009
- Palladium‐Catalyzed Tandem Heck Reaction/C-H Functionalization—Preparation of Spiro‐Indane‐OxindolesAngewandte Chemie-International Edition, 2008
- Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic AgentsAngewandte Chemie-International Edition, 2007
- On the Rearrangement of an Azaspiroindolenine to a Precursor to Phalarine: Mechanistic InsightsAngewandte Chemie-International Edition, 2007
- Enantioselective Total Synthesis of Convolutamydines B and EOrganic Letters, 2006
- Asymmetric Synthesis of Pyrrolidinoindolines. Application for the Practical Total Synthesis of (−)-PhenserineJournal of the American Chemical Society, 2004
- Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole AlkaloidsEuropean Journal of Organic Chemistry, 2003
- A novel and economical route to (±)-horsfiline using an aryl iodoazide tandem radical cyclisation strategyChemical Communications, 2001
- Simple indole alkaloids and those with a nonrearranged monoterpenoid unit (1999)Natural Product Reports, 2001
- A New Route to SpirooxindolesOrganic Letters, 2000