Oxindole Synthesis by Direct Coupling of C-H and C-H Centers
- 10 February 2009
- journal article
- research article
- Published by Wiley in Angewandte Chemie-International Edition
- Vol. 48 (9), 1636-1639
- https://doi.org/10.1002/anie.200805652
Abstract
An sp2/sp3 get-together: A novel and efficient method can be used to synthesize 3,3-disubstitued oxindoles by the direct intramolecular oxidative coupling of an aryl C H and a C H center (see scheme; DMF=N,N-dimethylformamide).Keywords
This publication has 58 references indexed in Scilit:
- Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic AgentsAngewandte Chemie-International Edition, 2007
- Natürliche Pyrrolidinylspirooxindole als Vorlagen für die Entwicklung medizinischer WirkstoffeAngewandte Chemie, 2007
- Rhodium‐Catalyzed Asymmetric Addition of Aryl‐ and Alkenylboronic Acids to IsatinsAngewandte Chemie-International Edition, 2006
- Rhodium‐Catalyzed Asymmetric Addition of Aryl‐ and Alkenylboronic Acids to IsatinsAngewandte Chemie, 2006
- Development of Chiral Nucleophilic Pyridine Catalysts: Applications in Asymmetric Quaternary Carbon SynthesisJournal of the American Chemical Society, 2003
- Catalytic Enantioselective Synthesis of Oxindoles and Benzofuranones That Bear a Quaternary StereocenterAngewandte Chemie-International Edition, 2003
- Catalytic Enantioselective Synthesis of Oxindoles and Benzofuranones That Bear a Quaternary StereocenterAngewandte Chemie, 2003
- Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole AlkaloidsEuropean Journal of Organic Chemistry, 2003
- Inter vs intramolecular amidoalkylations of aromatics - a new synthesis of oxindoles, isoquinolones and benzazepinonesTetrahedron Letters, 1980
- Substituted oxindole—ITetrahedron, 1968