The Implementation Chasm Hindering Genome-informed Health Care
- 1 March 2020
- journal article
- research article
- Published by Cambridge University Press (CUP) in The Journal of Law, Medicine & Ethics
- Vol. 48 (1), 119-125
- https://doi.org/10.1177/1073110520916999
Abstract
The promises of precision medicine are often heralded in the medical and lay literature, but routine integration of genomics in clinical practice is still limited. While the "last mile' infrastructure to bring genomics to the bedside has been demonstrated in some healthcare settings, a number of challenges remain - both in the receptivity of today's health system and in its technical and educational readiness to respond to this evolution in care. To improve the impact of genomics on health and disease management, we will need to integrate both new knowledge and new care processes into existing workflows. This change will be onerous and time-consuming, but hopefully valuable to the provision of high quality, economically feasible care worldwide.This publication has 64 references indexed in Scilit:
- Details on suicide among US physicians: data from the National Violent Death Reporting SystemGeneral Hospital Psychiatry, 2013
- Technical desiderata for the integration of genomic data into Electronic Health RecordsJournal of Biomedical Informatics, 2012
- Operational Implementation of Prospective Genotyping for Personalized Medicine: The Design of the Vanderbilt PREDICT ProjectClinical Pharmacology & Therapeutics, 2012
- Predicting warfarin dosage in European–Americans and African–Americans using DNA samples linked to an electronic health recordPharmacogenomics, 2012
- Returning Individual Research Results: Development of a Cancer Genetics Education and Risk Communication ProtocolJournal of Empirical Research on Human Research Ethics, 2010
- The “Meaningful Use” Regulation for Electronic Health RecordsThe New England Journal of Medicine, 2010
- Educating health-care professionals about genetics and genomicsNature Reviews Genetics, 2007
- Why Most Published Research Findings Are FalsePLoS Medicine, 2005
- Survey of Doctors' Experience of Patients Using the InternetJournal of Medical Internet Research, 2002
- The Quality of CareJAMA, 1988